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Of 11 patients with tuberous sclerosis complex(TSC)treated from 1980 to 1990 for obstructive hydrocephalus secondary to subependymal giant-cell astrocytoma,four had adequate documentation to determine visual outcome. Despite surgical relief of elevated intracranial pressure in all cases,two patients sustained further visual loss.In one patient,visual loss was arrested,and in one patient,it was prevented.Although hydrocephalus is uncommon in TSC,its effects on the optic nerves are serious and eventually irreversible.Because TSC patients may not be able to express early symptoms of increased intracranial pressure,periodic ophthalmologic examination and brain imaging may be advisable when a subependymal lesion has been identified. |
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astrocytoma
blindness
CAT scan,emission
hydrocephalus
hydrocephalus,non-communicating(obstructive)
intracranial pressure,increased
MRI
MRI,abnormal
neoplasm,primary of CNS
optic nerve,lesion of
papilledema
third ventricle,mass of
treatment of neurologic disorder
tuberous sclerosis
visual loss
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